Translational Research and Advanced Imaging Laboratory 

Magnetic Particle Imaging Conference, january the 28th, 14:00-15:00 RMSB

Magnetic Particle Imaging, A Novel Fast 3D In Vivo Imaging Modality based on Magnetic Nanoparticle Contrast Agents. Dr. Nicoleta Baxan, Bruker BioSpin MRI GmbH, Ettlingen, Germany

Magnetic particle imaging (MPI) is a novel tracer-based imaging method allowing in-vivo mapping and tracking of the spatial distribution of superparamagnetic iron oxide (SPIO) nanoparticles. It has been invented by Philips Research Laboratories Hamburg [1]. MPI is able to acquire quantitative 3D images of nanoparticle distribution with high temporal and spatial resolution by using a static magnetic field gradient (selection field) superposed by an oscillating homogenous magnetic field (drive field) and the reception of the tracer response. No anatomical signal background is obtained. The true real time imaging (46 frames per second) capabilities of MPI are offering direct applications in bolus tracking, cardiac and flow imaging. During this talk, an overview of the MPI technology will be presented covering also the technical specifications of the first commercially available Bruker MPI scanner. Initial results of rat/mouse cardiac MPI in vivo experiments are also described. 

 [1] B. Gleich, J. Weizenecker, Nature 2005, 435, 1214

 Invited by Gisèle Clofent-Sanchez, DR2 CNRS, Centre de Résonnance Magnétique des Systèmes Biologiques,

Dernière mise à jour vendredi 23 janvier 2015