Université de Bordeaux
LabEx TRAILCluster of Excellence
Cluster of excellence


Any publication issued from the TRAIL community must have the following sentence in the acknowledgments or in the financial support:

"This study was achieved within the context of the Laboratory of Excellence TRAIL ANR-10-LABX-57."


Latest TRAIL publications (2019):

WP2 - New sequences


  • Faller, T.L., Trotier, A.J., Miraux, S. et al., Radial MP2RAGE sequence for rapid 3D T1 mapping of mouse abdomen: application to hepatic metastases, Eur Radiol (2019). Read here


ONCOFLUX project:

  • Crémillieux Y, Dumont U, Mazuel L, Salvati R, Zhendre V, Rizzitelli S, Blanc J, Roumes H, Pinaud N and Bouzier-Sore A-K (2019) Online Quantification of Lactate Concentration in Microdialysate During Cerebral Activation Using 1H-MRS and Sensitive NMR Microcoil. Front. Cell. Neurosci. 13:89. Read here
  • Yannick Crémillieux, Yoann Montigaud, Clémence Bal, Noël Pinaud, Vi Pham, Sophie Perine, Marco Natuzzi, François Lux, Olivier Tillement, Nobuyasu Ichinose, Bei Zhang, Jérémie Pourchez, Three‐dimensional quantitative MRI of aerosolized gadolinium‐based nanoparticles and contrast agents in isolated ventilated porcine lungs, Magnetic Resonance in Medicine, oct 2019 Read here

WP4 - Tracers and contrast agents

FITTING project:

  • Zoeisha S. Chinoy, Clément Bodineau, Camille Favre, Kelley W. Moremen, Raúl V. Durán and Frédéric Friscourt, Selective Engineering of Linkage-Specific α2,6-N-Linked Sialoproteins Using Sydnone-Modified Sialic Acid Bioorthogonal Reporters, Angewandte Chemie International Edition, 2019, 58, 4281-4285. Read here

PRITOR project:

  • Morgat C., Schollhammer R., Macgrogan G., Barthe N., Vélasco V., Vimont D., et al. (2019) Comparison of the binding of the gastrin-releasing peptide receptor (GRP-R) antagonist 68Ga-RM2 and 18F-FDG in breast cancer samples. PLoS ONE 14(1):e0210905. Read here
  • Clément Morgat, Adrien Chastel, Vincent Molinie, Romain Schollhammer, Gaétan Macgrogan, Valérie Vélasco, Bernard Malavaud, Philippe Fernandez and Elif Hindié, Neurotensin Receptor-1 Expression in Human Prostate Cancer: A Pilot Study on Primary Tumors and Lymph Node Metastases, International journal of molecular sciences, April 2019, 20(7), 1721 Read here
  • Romain Schollhammer, Henri De Clermont Gallerande, Mokrane Yacoub, Marie-Laure Quintyn Ranty, Nicole Barthe, Delphine Vimont, Elif Hindié, Philippe Fernandez and Clément Morgat, Comparison of the radiolabeled PSMAinhibitor 111In-PSMA-617 and the radiolabeled GRP-R antagonist 111In-RM2 in primary prostate cancer samples, EJNMMI Research, 019, 9: 52 Read here

SUPSIFLU project:

  • Morgan Cormier, Eric Fouquet and Philippe Hermange, Expedient synthesis of a symmetric cycloheptyne-Co2(CO)6 complex for orthogonal Huisgen cycloadditions,  Organic Chemistry Frontier, April 2019, 2019,6, 1114-1117 Read here

TARGLIN project:

  • Konate K, Dussot M, Aldrian G, Vaissière A, Viguier V, Ferreiro Neira I, Couillaud F, Vivès E, Boisguerin P & Deshayes S (2018). Peptide-based nanoparticles to rapidly and efficiently “Wrap’n Roll” siRNA into cells. Bioconjug Chem Read here

WP5 - Biological bioimaging markers

BRAIN-RESV project:

  • Ursule Dumont, Stéphane Sanchez, Benjamin Olivier, Jean-François Chateil, Luc Pellerin, Marie-Christine Beauvieux, Anne-Karine Bouzier-Sore, Hélène Roumes, Maternal consumption of piceatannol: A nutritional neuroprotective strategy against hypoxia-ischemia in rat neonates, Brain research, 2019 Aug 15;1717:86-94 Read here

GMCOG project:

  • Jason H. Su, Francis T. Thomas, Willard S. Kasoff, Thomas Tourdias, Eun Young Choi, Brian K. Rutt and Manojkumar Saranathan, Thalamus Optimized Multi Atlas Segmentation (THOMAS): fast, fully automated segmentation of thalamic nuclei from structural MRI. NeuroImage, 2019, 194, 272-282. Read here
  • Koubiyr, I., Deloire, M., Besson, P., Coupé, P., Dulau, C., Pelletier, J., Tourdias T., Audoin B., Brochet B., Ranjeva J.-P., and Ruet, A. (2018). Longitudinal study of functional brain network reorganization in clinically isolated syndrome, Multiple Sclerosis Journal Read here
  • Planche V, Su J, Mournet S, Saranathan M, Dousset V, Han M, Rutt B and Tourdias T, White-matter-nulled MPRAGE at 7T reveals thalamic lesions and atrophy of specific thalamic nuclei in multiple sclerosis. Multiple Sclerosis Journal, 2019 Read here
  • Ismail Koubiyr, Pierre Besson, Mathilde Deloire, Julie Charre-Morin, Aurore Saubusse, Thomas Tourdias, Bruno Brochet and Aurélie Ruet, Dynamic modular-level alterations of structural-functional coupling in clinically isolated syndrome, Brain, sept 2019 Read here

INNES project:

  • Stephen F.Carter, Karl Herholz, Pedro Rosa-Neto, Luc Pellerin, Agneta Nordberg, Eduardo R.Zimmer, Astrocyte Biomarkers in Alzheimer’s Disease, Trends in Molecular Medicine (2019) 1397 1-19 Read here
  • Sarah Geller, Yoan Arribat, Citlalli Netzahualcoyotzi, Sylviane Lagarrigue, Lionel Carneiro, Lianjun Zhang, Francesca Amati, Isabel C. Lopez-Mejia, and Luc Pellerin,Tanycytes Regulate Lipid Homeostasis by Sensing Free Fatty Acids and Signaling to Key Hypothalamic Neuronal Populations via FGF21 Secretion, Cell Metabolism, Sept 2019 Read here

  • Bessem Mornagui, Raja Rezg, Cendrine Repond, Luc Pellerin, Effects of bisphenol S, a major substitute of bisphenol A, on neurobehavioral responses and cerebral monocarboxylate transporters expression in mice, Food and chemical toxicology, sept 2019 Read here


  • Kirubanandhan Lokeshwaran, Audrey Hemadou, N.S. Jayaprakash, R.R. Prasanna, Marie-Josée Jacobin-Valat, Wilfrid Dieryck, Gilles Joucla, M.A. Vijayalakshmi, Gisèle Clofent-Sanchez, Xavier Santarelli, Krishnan Venkataraman, Development of anti-chloro 192 tyrosine HDL apoA-I antibodies for the immunodiagnosis of cardiovascular diseases,  Journal of Immunological Methods, oct 2019 Read here

STEAMRI project:

  • Ilyes Benlala, MD, Patrick Berger, MD, PhD, Pierre-Olivier Girodet, MD, PhD, Claire Dromer, MD, Julie Macey, MD, François Laurent, MD, Gaël Dournes, MD, PhD, Automated Volumetric Quantification of Emphysema Severity by Using Ultrashort Echo Time MRI: Validation in Participants with Chronic Obstructive Pulmonary Disease, Radiology, 2019 Jun 4:190052 Read here

WP6 - Mathematical simulation and modeling


  • Pierrick Coupé, José Vicente Manjón, Enrique Lanuza & Gwenaelle Catheline, Lifespan Changes of the Human Brain In Alzheimer’s Disease, Nature Scientific Report, May 2019, 9:3998 Read here
  • Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification, Kilian Hett, Vinh-Thong Ta, Gwenaëlle Catheline, Thomas Tourdias, José V. Manjón, Pierrick Coupé, Alzheimer’s Disease Neuroimaging Initiative, oct 2019 Nature Scientific Reports Read here

  • Pierrick Coupé, Boris Mansencal, Michaël Clément, Rémi Giraud, Baudouin Denis de Senneville, Vinh-Thong Ta, Vincent Lepetit and José V. Manjon, AssemblyNet: A Novel Deep Decision-Making Process for Whole Brain MRI Segmentation, MICCAI, oct 2019 Read here


  • Pierre Antoine Linck, Gregory Kuchcinski, Fanny Munsch, Romain Griffier, Renaud Lopes, Gosuke Okubo, Sharmila Sagnier, Pauline Renou, Julien Asselineau, Paul Perez, Vincent Dousset, Igor Sibon, Thomas Tourdias, Neurodegeneration of the Substantia Nigra after Ipsilateral Infarct: MRI R2* Mapping and Relationship to Clinical Outcome, Radiology 2019; 291:438–448. Read here
  • Aurélien Olivier, Olivier Moal, Bertrand Moal, Fanny Munsch, Gosuke Okubo, Igor Sibon, Vincent Dousset, Thomas Tourdias, Active learning strategy and hybrid training for infarct segmentation on diffusion MRI with a U-shaped network, Journal of Medical Imaging, oct 2019 Read here

MOD project:

  • Crombé A, Périer C, Kind M, De Senneville BD, Le Loarer F, Italiano A, Buy X, Saut O, T2-based MRI Delta-radiomics improve response prediction in soft-tissue sarcomas treated by neoadjuvant chemotherapy, Journal of Magnetic Resonance Imaging (2018) Read here

WP7 - Cohort imaging methodology

ACTE project:

  • G. Di Scala, M. Dupuy, E. Guillaud, E. Doat, E. Barse, B. Dillhareguy, F.A.M. Jean, M. Audiffren, J.R. Cazalets & S. Chanraud (2019): Efficiency of Sensorimotor Networks: Posture and Gait in Young and Older Adults, Experimental Aging Research Read here

COBRASCAN project:

  • Coste F, Benlala I, Dournes G, Dromer C, Blanchard E, Girodet P-O, Montaudon M, Baldacci F, Picard F, Marthan R, Laurent F, Berger P, Quantitative CT assessment of bronchial and vascular alterations in severe precapillary pulmonary hypertension, International Journal COPD, 2019